| | Statistic | FOR | OPP |
| Total Yards per Game | 409.0 | 251.5 |
| Rushing YDS per ATT | 4.5 | 3.8 |
| Passing YDS per ATT | 8.0 | 5.3 |
| Passing Comp % | 0.771 | 0.514 |
| Total YDS per Play | 6.4 | 4.7 |
| Total YDS per Point | 16.4 | 19.3 |
|
| Injury |
| [LB] 09/21/2021 - Bradley Chubb is out indefinitely ( Ankle ) |
| [LB] 09/21/2021 - Josey Jewell IR ( Shoulder ) |
| [OL] 09/19/2021 - Graham Glasgow is "?" Sunday vs NY Jets ( Heart ) |
| [CB] 09/14/2021 - Ronald Darby IR ( Hamstring ) |
| [WR] 09/14/2021 - Jerry Jeudy IR ( Ankle ) |
| [RB] 09/06/2021 - LeVante Bellamy IR ( Ankle ) |
| [CB] 09/06/2021 - Michael Ojemudia IR ( Hamstring ) |
| [RB] 09/06/2021 - Mike Boone IR ( Quad ) |
| [OL] 09/06/2021 - Cody Conway IR ( Knee ) |
| [C] 09/06/2021 - Brett Jones IR ( Biceps ) |
| [LB] 09/06/2021 - Natrez Patrick IR ( Leg ) |
| [RB] 09/06/2021 - Adrian Killins Jr. IR ( Ankle ) |
