| | Statistic | FOR | OPP |
| Total Yards per Game | 294.0 | 320.5 |
| Rushing YDS per ATT | 4.1 | 4.2 |
| Passing YDS per ATT | 5.6 | 6.6 |
| Passing Comp % | 0.557 | 0.708 |
| Total YDS per Play | 5.0 | 5.5 |
| Total YDS per Point | 29.4 | 14.6 |
|
| Injury |
| [LB] 09/24/2021 - Jamien Sherwood is probable Sunday vs Denver ( Ankle ) |
| [WR] 09/24/2021 - Jamison Crowder is doubtful Sunday vs Denver ( Groin ) |
| [DE] 09/24/2021 - John Franklin-Myers is "?" Sunday vs Denver ( Calf ) |
| [RB] 09/24/2021 - Tevin Coleman is OUT Sunday vs Denver ( Illness ) |
| (!)[QB] 09/22/2021 - Zach Wilson is probable Sunday vs Denver ( Groin ) |
| [T] 09/13/2021 - Mekhi Becton IR ( Knee ) |
| [LB] 09/13/2021 - Blake Cashman is out indefinitely ( Hamstring ) |
| [S] 09/12/2021 - Lamarcus Joyner is out for season ( Triceps ) |
| [P] 09/12/2021 - Braden Mann is out indefinitely ( Knee ) |
| [S] 09/11/2021 - Sharrod Neasman IR ( Hamstring ) |
| [DE] 09/06/2021 - Carl Lawson IR ( Achilles ) |
| [CB] 09/06/2021 - Zane Lewis IR ( Pectoral ) |
| [OL] 09/06/2021 - Conor McDermott IR ( Knee ) |
| [LB] 09/06/2021 - Jarrad Davis IR ( Ankle ) |
| [CB] 09/06/2021 - Corey Ballentine IR ( Knee ) |
| [OL] 09/06/2021 - Parker Ferguson IR ( Undisclosed ) |
| [OL] 09/06/2021 - Teton Saltes IR ( Knee ) |
| [OL] 09/06/2021 - Cameron Clark IR ( Back ) |
| [S] 09/06/2021 - Ashtyn Davis IR ( Foot ) |
| [DE] 08/25/2021 - Vinny Curry is out for season ( Medical ) |
| [G] 08/18/2021 - Alex Lewis is out for season ( Retired ) |
