| | Statistic | FOR | OPP |
| Total Yards per Game | 386.0 | 399.5 |
| Rushing YDS per ATT | 3.8 | 3.0 |
| Passing YDS per ATT | 7.4 | 6.5 |
| Passing Comp % | 0.651 | 0.726 |
| Total YDS per Play | 6.4 | 5.5 |
| Total YDS per Point | 9.8 | 14.8 |
|
| Injury |
| [LB] 09/20/2021 - Kevin Minter is "?" Sunday vs LA Rams ( COVID-19 ) |
| [WR] 09/19/2021 - Jaydon Mickens is "?" Sunday vs LA Rams ( Hip ) |
| [CB] 09/13/2021 - Sean Murphy-Bunting IR ( Elbow ) |
| [LS] 09/13/2021 - Zach Triner IR ( Finger ) |
| [G] 09/06/2021 - John Molchon IR ( Leg ) |
| [G] 09/06/2021 - Sadarius Hutcherson IR ( Knee ) |
| [S] 09/06/2021 - Curtis Riley IR ( Achilles ) |
| [C] 09/06/2021 - Donell Stanley IR ( Undisclosed ) |
| [T] 09/06/2021 - Brad Seaton IR ( Undisclosed ) |
| [LB] 09/03/2021 - Cam Gill IR ( Leg ) |