| | Statistic | FOR | OPP |
| Total Yards per Game | 326.5 | 297.5 |
| Rushing YDS per ATT | 4.2 | 4.2 |
| Passing YDS per ATT | 6.2 | 6.2 |
| Passing Comp % | 0.739 | 0.583 |
| Total YDS per Play | 5.3 | 5.2 |
| Total YDS per Point | 15.9 | 25.9 |
|
| Injury |
| [T] 09/26/2021 - Trent Brown is downgraded to OUT Sunday vs New Orleans ( Calf ) |
| [S] 09/26/2021 - Adrian Phillips is probable Sunday vs New Orleans ( Undisclosed ) |
| [LB] 09/26/2021 - Josh Uche is downgraded to OUT Sunday vs New Orleans ( Back ) |
| [LB] 09/24/2021 - Kyle Van Noy is probable Sunday vs New Orleans ( Throat ) |
| [LB] 09/24/2021 - Matt Judon is upgraded to probable Sunday vs New Orleans ( Knee ) |
| [PK] 09/23/2021 - Quinn Nordin IR ( Abdominal ) |
| [WR] 09/11/2021 - Malcolm Perry IR ( Foot ) |
| [LB] 09/06/2021 - Anfernee Jennings IR ( Undisclosed ) |
| [TE] 09/06/2021 - Dalton Keene IR ( Knee ) |
| [TE] 09/06/2021 - Troy Fumagalli IR ( Undisclosed ) |
| [LB] 09/06/2021 - Raekwon McMillan IR ( Knee ) |
| [WR] 09/02/2021 - N'Keal Harry IR ( Shoulder ) |
| [CB] 08/31/2021 - Stephon Gilmore PUP ( Quad ) |
| [QB] 07/30/2021 - Jarrett Stidham is out indefinitely ( Back ) |
